Aryloxy fluoroacetic acids 3a-3h – fluorine analogs of phenoxyacetic herbicides 2,4-D, MCPA, 2,4,5-T, and 4-CPA were efficiently synthesized in 29–88% yield, using appropriate phenols and either bromodifluoro- or bromofluoroacetic acid in the presence of sodium hydride as a base and in either dioxane or THF as solvents. Fluorine derivatives of 2,4-D (3a, 3b) show herbicidal activity against three weed species. Parent herbicides 2,4-D, MCPA, 2,4,5-T, 4-CPA, monofluorine derivatives of MCPA (3d) and 2,4,5-T (3f) show fungistatic activity against phytopatogenic fungi species Phytophtora cactorum.

中文翻译：

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苯氧基乙酸除草剂的氟类似物的除草和抑菌特性

芳氧基氟乙酸3a - 3h –苯氧基乙酸除草剂2,4-D，MCPA，2,4,5-T和4-CPA的氟类似物可以通过使用适当的酚和溴代二氟或苯酚高效合成，产率为29-88％。以氢化钠为碱，以二恶烷或THF为溶剂，以溴氟乙酸为溶剂。2,4-D（3a，3b）的氟衍生物显示出对三种杂草物种的除草活性。母体除草剂2,4-d，MCPA，2,4,5-T，4-CPA，MCPA（的monofluorine衍生物3D）和2,4,5-T（3F）显示出抗真菌phytopatogenic物种抑真菌活性疫恶疫霉。