In this study, a modified quick, easy, cheap, efficient, rugged and safe (QuEChERS) method coupled with gas chromatography with flame photometric detection (GC–FPD) was developed for the determination of 44 organophosphorous pesticide (OPP) residues in 44 batches of Pogostemon cablin and its related products for the first time. The QuEChERS extraction conditions were optimized, and the matrix effect that may influence recoveries was evaluated and minimized by matrix-matched calibration curves. Under the optimized conditions, the calibration curves for all OPPs showed good linearities in the concentration range of 0.04–1.5 μg mL⁻¹ with correlation coefficients better than 0.9909. The limits of detection were in the range of 0.004–0.02 μg mL⁻¹ and quantification were 0.01–0.04 μg mL⁻¹, below the regulatory maximum residue limits suggested. Mean recoveries ranged between 76.62 and 113.7% (99.34% on average), and relative standard deviation was 3.71% on average. The validated method was applied on 44 real samples including P. cablin, and P. cablin oil and powder. Two (4.5%) samples were found to be contaminated by chlorpyrifos with levels below the legal limits, which were successfully confirmed by gas chromatography–mass spectrometry (GC–MS). Based on the results, the developed method was proved to be simple, fast, accurate, low cost and environmentally friendly and can be successfully applied in the determination of targeted OPP residues in P. cablin and its related products. Moreover, it also attaches great importance to pesticide monitoring programs in food, soil and air in the future.

在这项研究中，开发了一种改进的快速，简便，廉价，高效，坚固和安全（QuEChERS）方法，并结合气相色谱-火焰光度检测（GC-FPD）方法来测定44批次中的44种有机磷农药（OPP）残留量的广藿香和其相关产品的第一次。优化了QuEChERS提取条件，并通过基质匹配的校准曲线评估了可能影响回收率的基质效应。在最佳条件下，所有OPP的校准曲线在0.04–1.5μgmL ^-1的浓度范围内均显示出良好的线性，相关系数优于0.9909。检测限在0.004–0.02μgmL ^-1范围内定量为0.01–0.04μgmL ^-1，低于建议的最大残留限量。平均回收率在76.62和113.7％之间（平均99.34％），相对标准偏差平均为3.71％。经验证的方法适用于44个真实样品，包括赤霞珠和赤霞珠油和粉末。发现有两个（4.5％）样品被毒死rif污染，其含量低于法定限值，并通过气相色谱-质谱（GC-MS）成功确认。结果表明，所开发的方法简便，快速，准确，成本低廉，环境友好，可成功地用于卡伯林中目标OPP残留的测定。及其相关产品。此外，它也非常重视将来在食品，土壤和空气中的农药监测计划。