Reaction of Isatins with 6-Amino Uracils and Isoxazoles: Isatin Ring-Opening vs. Annulations and Regioselective Synthesis of Isoxazole fused Quinoline Scaffolds in Water,Green Chemistry

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Reaction of Isatins with 6-Amino Uracils and Isoxazoles: Isatin Ring-Opening vs. Annulations and Regioselective Synthesis of Isoxazole fused Quinoline Scaffolds in Water
Green Chemistry ( IF 9.3 ) Pub Date : 2015-04-08 00:00:00 , DOI: 10.1039/c5gc00006h
Nataraj Poomathi _{1,

2,

3,

4} , Sivakalai Mayakrishnan _{1,

2,

3,

4} , Doraiswamy Muralidharan _{1,

2,

3,

4} , Rajagopal Srinivasan _{2,

3,

4,

5} , Paramasivan T. Perumal _{1,

2,

3,

4}

Affiliation

A green and efficient straightforward approach for the regioselective synthesis of novel isoxazolo[5,4-b]quinolin-4-yl)pyrimidine-2,4(1H,3H)-diones and isoxazolo[5,4-b]quinolin-4-yl)-1H-pyrazol-5-amines via the cleavage of the isatin C-N bond followed by ring expansion reaction in one-pot...

中文翻译：

Isatins与6-氨基尿嘧啶和异恶唑的反应：Isatin开环vs.环和异恶唑稠合喹啉骨架在水中的区域选择性合成

新型异恶唑啉[5,4-b]喹啉-4-基）嘧啶-2,4（1H，3H）-二酮和异恶唑啉[5,4-b]喹啉-4的区域选择性合成的绿色高效简单方法-Isyl）-1H-pyrazol-5-amines by isatin CN bond裂解，然后在一锅中进行扩环反应。

更新日期：2015-04-09

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