A variety of polymerizable lipids derived from hexacosa-10,12-diynoic acid and hexacosa-10,12-diyne-1-ol have been synthesized and spread at the gas/water interface. The measured surface pressure/area isotherms indicate that head group charge and bulkiness have strong influences on the area occupied per molecule. In the case of zwitterionic phospholipids additional area changes are brought about by alkaline and acidic subphases, which is probably due to an alteration of head group conformation. Condensed state diacetylenic lipid monolayers in a nitrogen atmosphere are polymerizable by UV irradiation. The polymerization reaction was monitored at the gas/water interface by the area change at constant surface pressure and the change of optical density in the visible region. As already observed for vesicle polymerization, single chain amphiphiles exhibit a different absorption behavior than asymmetric double chain amphiphiles of the phosphoglycerol type. The polymerized monolayers were more densely packed and more stable than their monomeric counterparts as indicated by the smaller areas and higher pressures reached before the collapse points.

中文翻译：

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二乙炔类磷脂在气-水界面处的扩散和聚合行为。

合成了多种衍生自己六醇-10,12-二炔酸和己六醇-10,12-二炔-1-醇的可聚合脂质，并在气/水界面处扩散。测得的表面压力/面积等温线表明，头基电荷和体积对每个分子占据的面积有很大影响。在两性离子磷脂的情况下，碱性和酸性亚相引起额外的面积变化，这可能是由于头基构象的改变。氮气氛下的缩合状态的二炔类脂质单层可通过紫外线照射而聚合。通过在恒定表面压力下的面积变化和可见光区域的光密度变化，在气/水界面处监测聚合反应。如已经在囊泡聚合中观察到的，单链两亲物表现出与磷酸甘油型不对称双链两亲物不同的吸收行为。聚合的单分子层比其单体对应物更紧密地堆积并且更稳定，这是由较小的面积和在坍缩点之前达到的较高压力所表明的。