Three new kinds of 1,3,5-thiadiazine-2-thione derivatives of chitosan with two different molecular weight (SATTCS1, SATTCS2, TITTCS1, TITTCS2, CITTCS1 and CITTCS2) have been prepared. Their structures were characterized by IR spectroscopy. The substitution degree of derivatives calculated by elemental analyses was 0.47, 0.42, 0.41, 0.38, 0.41 and 0.36, respectively. The result shows that substitution degree of derivatives was higher with lower molecular weight. The antioxidant activity was studied using an established system, such as hydroxyl radical scavenging, superoxide radical scavenging and reducing power. Antioxidant activity of the 1,3,5-thiadiazine-2-thione derivatives of chitosan were stronger than that of chitosans and antioxidant activity of low molecular weight derivatives were stronger than that of high molecular weight derivatives. It is a potential antioxidant in vitro.

中文翻译：

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壳聚糖的1,3,5-噻二嗪-2-硫酮衍生物的制备及其体外抗氧化活性

制备了三种具有两种不同分子量的壳聚糖的新型1,3,5-噻二嗪-2-硫酮衍生物（SATTCS1，SATTCS2，TITTCS1，TITTCS2，CITTCS1和CITTCS2）。通过红外光谱对它们的结构进行了表征。通过元素分析计算出的衍生物的取代度分别为0.47、0.42、0.41、0.38、0.41和0.36。结果表明，较低的分子量，衍生物的取代度较高。使用建立的体系，例如清除羟自由基，清除超氧自由基和还原能力，研究了抗氧化活性。壳聚糖的1,3,5-噻二嗪-2-硫酮衍生物的抗氧化活性强于壳聚糖，低分子量衍生物的抗氧化活性强于高分子量衍生物。