Synthesis of novel and uniquely shaped 3-azabicyclo[4.2.0]octan-4-one derivatives by sequential Ugi/[2+2] ene-enone photocycloadditions.,Organic Letters

当前位置： X-MOL 学术 › Org. Lett. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Synthesis of novel and uniquely shaped 3-azabicyclo[4.2.0]octan-4-one derivatives by sequential Ugi/[2+2] ene-enone photocycloadditions.
Organic Letters ( IF 4.9 ) Pub Date : 2007 Mar 29 , DOI: 10.1021/ol070164l
Irini Akritopoulou-Zanze ₁ , Alan Whitehead ₁ , Jan E. Waters ₁ , Rodger F. Henry ₁ , Stevan W. Djuric ₁

Affiliation

[structure: see text]. We report a new methodology for the construction of novel and uniquely shaped 3-azabicyclo[4.2.0]octan-4-one derivatives by combining the Ugi multicomponent reaction with [2+2] enone-olefin photochemical transformations. The overall sequence is capable of creating up to five stereocenters; however, in most cases, only two diastereomers are observed.

中文翻译：

通过顺序的Ugi / [2 + 2]烯-烯酮光环加成反应合成新颖且形状独特的3-氮杂双环[4.2.0] octan-4-one衍生物。

[结构：见文字]。我们报告了通过结合[2 + 2]烯酮-烯烃光化学转化的Ugi多组分反应，构造新颖且形状独特的3-氮杂双环[4.2.0] octan-4-one衍生物的新方法。整个序列最多可以创建五个立体中心。但是，在大多数情况下，仅观察到两个非对映异构体。

更新日期：2017-01-31

点击分享查看原文

点击收藏

阅读更多本刊新发论文本刊介绍/投稿指南