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Amphiphilic Peptide Self-Assembly: Expansion to Hybrid Materials
Biomacromolecules ( IF 5.5 ) Pub Date : 2017-08-10 00:00:00 , DOI: 10.1021/acs.biomac.7b00764
Viktoria Mikhalevich 1 , Ioana Craciun 1 , Myrto Kyropoulou 1 , Cornelia G. Palivan 1 , Wolfgang Meier 1
Affiliation  

The design of functional systems with sizes in the nanometer range is a key challenge in fields such as biomedicine, nanotechnology, and engineering. Some of the most promising materials nowadays consist of self-assembling peptides or peptide–polymer hybrid materials because of their versatility and the resulting properties that can be achieved with these structures. Self-assembly of pure amphiphilic peptides or in combination with block copolymers results in a large variety of nanostructures (micelles, nanoparticles (NPs), compartments, planar membranes) each with different characteristics and tunable properties. Here, we describe such novel peptide- or peptide–polymer-based supramolecular nanostructures and emphasize their functionality and various promising applications.

中文翻译:

两亲性肽自组装:扩展到混合材料。

具有纳米范围大小的功能系统的设计是诸如生物医学,纳米技术和工程学等领域的关键挑战。如今,一些最有前途的材料由自组装肽或肽-聚合物杂化材料组成,这是因为它们的多功能性以及这些结构可以实现的最终特性。纯两亲性肽的自组装或与嵌段共聚物的结合会产生多种纳米结构(胶束,纳米颗粒(NP),隔室,平面膜),每种具有不同的特性和可调节的特性。在这里,我们描述了这种新颖的基于肽或肽聚合物的超分子纳米结构,并强调了它们的功能和各种有前途的应用。
更新日期:2017-08-10
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