The continuous demand for novel hybrid materials in specific technological applications inspires people to develop new synthetic strategies in a modular and efficient way. In the recent years, extensive efforts have been devoted to using polyhedral oligomeric silsesquioxane (POSS) to construct multifunctional nanohybrids and nanocomposites with tunable hierarchical structures and unparalleled properties. The shape-persistent nanostructure and diverse surface chemistry make those nanocaged materials ideal building blocks for such purposes. Functionalization of POSS cages are further facilitated by the introduction of “click” chemistry at the beginning of this century. “Click” reactions include several kinds of selective and orthogonal chemical ligations with high efficiency under mild reaction conditions. The concept has generated real stimulus not only in elegantly preparing materials of choice, but in making the leap from laboratory to industrial scale-up of POSS-based hybrid materials as well.

在特定技术应用中对新型混合材料的不断需求激发了人们以模块化和高效的方式开发新的合成策略。近年来，人们致力于使用多面体低聚倍半硅氧烷（POSS）来构建具有可调层次结构和无与伦比性能的多功能纳米杂化物和纳米复合材料。形状持久的纳米结构和多样的表面化学特性使这些纳米笼状材料成为实现此类目的的理想构建基块。在本世纪初，“点击”化学的引入进一步促进了POSS笼的功能化。“点击”反应包括在温和的反应条件下高效进行的几种选择性和正交化学连接。