1,2,3,4,6-Penta-O-Galloyl-β-d-Glucose (PGG) is a hydrolysable tannin that belongs to the group of gallotannins but also participates in the formation of ellagitannins. PGG is composed of five galloyl groups with a glucose at its core and has structural characteristics that confer a high biological power. In this paper, we describe the chemistry of PGG, which is analyzed from a critical point regarding the types of synthesis, new sources of production from plants and by-products, highlighting the PGG obtaining, and its main functional properties recently reported in scientific literature. PGG has attracted attention because of its therapeutic potential and has shown functional properties as antimicrobial, anti-inflammatory, anti-carcinogenic, antidiabetic and antioxidant. Bioconversion from tannic acid can be potentialized with the use of biotechnological techniques. PGG can be obtained from natural sources as by-products. Research should continue to obtain pure molecules, in adequate quantity and with great biological activity.

1,2,3,4,6-五-O-Galloyl-β- d-葡萄糖（PGG）是一种可水解的单宁，它属于没食子鞣质，但也参与鞣花单宁的形成。PGG由五个以葡萄糖为核心的没食子酰基基团组成，并且具有赋予高生物力的结构特征。在本文中，我们描述了PGG的化学性质，从关键角度分析了PGG的化学性质，重点涉及合成类型，植物和副产物的新生产来源，重点介绍了PGG的获得及其主要功能特性，这些文献最近在科学文献中已有报道。 。PGG由于其治疗潜力而备受关注，并已显示出抗微生物，抗炎，抗致癌，​​抗糖尿病和抗氧化剂的功能特性。单宁酸的生物转化可以利用生物技术技术来实现。PGG可以作为副产物从天然来源获得。研究应继续获得足够数量且具有良好生物学活性的纯分子。