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Kadsuphilactones A and B, two new triterpene dilactones from kadsuraphilippinensis.
Organic Letters ( IF 4.9 ) Pub Date : 2005 Jul 21 , DOI: 10.1021/ol051155k Ya-Ching Shen , Yu-Chi Lin , Michael Y. Chiang , Sheau Farn Yeh , Yuan-Bin Cheng , Chia-Ching Liao
Organic Letters ( IF 4.9 ) Pub Date : 2005 Jul 21 , DOI: 10.1021/ol051155k Ya-Ching Shen , Yu-Chi Lin , Michael Y. Chiang , Sheau Farn Yeh , Yuan-Bin Cheng , Chia-Ching Liao
[structure: see text]. Two novel triterpene dilactones, kadsuphilactones A (1) and B (2), were isolated from the Taiwanese medicinal plant Kadsura philippinensis. The structures of 1 and 2 were elucidated on the basis of extensive spectroscopic methods, including two-dimensional NMR techniques, and confirmed by X-ray crystallographic analysis. Kadsuphilactone B (2) exhibited in vitro anti-HBV activity with IC(50) values of 6 microg/mL by HBsAg enzyme immunoassay.
更新日期：2017-01-31
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