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A Simple, Cleated DNA Walker That Hangs on to Surfaces
ACS Nano ( IF 15.8 ) Pub Date : 2017-07-18 00:00:00 , DOI: 10.1021/acsnano.7b02693 Cheulhee Jung 1 , Peter B. Allen 2 , Andrew D. Ellington 1
ACS Nano ( IF 15.8 ) Pub Date : 2017-07-18 00:00:00 , DOI: 10.1021/acsnano.7b02693 Cheulhee Jung 1 , Peter B. Allen 2 , Andrew D. Ellington 1
Affiliation
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We designed and demonstrated a single-legged or unipedal walker that has a “cleat” that allows it to persistently associate with a track and make autonomous decisions about movement. The walker is highly processive over long periods of time, as shown by its movement over a microparticle surface suffused with substrate. The simple design can be readily optimized on the basis of simple energetic considerations. The walker can be used for signal amplification and should prove especially valuable for programming amorphous computations within chemical reaction networks.
中文翻译：
悬挂在表面的简单的带顶棚的DNA Walker
我们设计并演示了一种单腿或单足步行器，该步行器具有“锁止装置”，可以使其与赛道保持永久关联并就运动做出自主决定。助行器在长时间内具有高度的处理能力，如其在充满底物的微粒表面上的移动所示。基于简单的能量考虑，可以容易地优化简单的设计。沃克可用于信号放大，并且对于在化学反应网络内对非晶计算进行编程应被证明特别有价值。
更新日期：2017-07-18
中文翻译：
悬挂在表面的简单的带顶棚的DNA Walker
我们设计并演示了一种单腿或单足步行器，该步行器具有“锁止装置”，可以使其与赛道保持永久关联并就运动做出自主决定。助行器在长时间内具有高度的处理能力，如其在充满底物的微粒表面上的移动所示。基于简单的能量考虑，可以容易地优化简单的设计。沃克可用于信号放大，并且对于在化学反应网络内对非晶计算进行编程应被证明特别有价值。
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