Palladium-catalyzed rearrangement/arylation of 2-allyloxypyridine leading to the synthesis of N-substituted 2-pyridones.,Organic Letters

当前位置： X-MOL 学术 › Org. Lett. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Palladium-catalyzed rearrangement/arylation of 2-allyloxypyridine leading to the synthesis of N-substituted 2-pyridones.
Organic Letters ( IF 4.9 ) Pub Date : 2003 Jun 12 , DOI: 10.1021/ol0346234
Kenichiro Itami ₁ , Daisuke Yamazaki ₁ , Jun-ichi Yoshida ₁

Affiliation

[reaction: see text] The Pd-catalyzed one-pot rearrangement/arylation of 2-allyloxypyridine is described. The catalyst/base combination of Pd[P(t-Bu)(3)](2)/Ag(2)CO(3) was found to be optimal for this one-pot rearrangement/arylation. The initial rearrangement of 2-allyloxypyridine was found to be catalyzed by both Pd(0) and Pd(II) complexes with different mechanisms.

中文翻译：

钯催化的2-烯丙氧基吡啶的重排/芳基化反应导致N-取代的2-吡啶酮的合成。

[反应：见正文]描述了Pd催化的2-烯丙氧基吡啶的一锅重排/芳基化反应。发现Pd [P（t-Bu）（3）]（2）/ Ag（2）CO（3）的催化剂/碱组合对于这种一锅重排/芳构化是最佳的。发现2-烯丙氧基吡啶的初始重排被具有不同机理的Pd（0）和Pd（II）复合物催化。

更新日期：2017-01-31

点击分享查看原文

点击收藏

阅读更多本刊新发论文本刊介绍/投稿指南