A new one-pot nitration employing tetramethylammonium nitrate and trifluoromethanesulfonic anhydride in dichloromethane to provide a ready source of the nitronium triflate nitrating agent is presented. Rapid and selective nitration with a variety of aromatic and heteroaromatic substrates is achieved resulting in the synthesis of several novel organic compounds. A distinct advantage is the removal of undesired byproducts by aqueous workup. This very mild nitration permits large-scale syntheses and gives high isolated product yields that often require no further purification. This tetramethylammonium nitrate-based nitration also has been applied to microwave-assisted conditions, and the results with several compounds are outlined.

中文翻译：

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亲电四烷基硝酸铵硝化。二。用硝酸四甲基铵和三氟甲磺酸酐改进无水芳族和杂芳族单硝化反应，包括选定的微波实例。

提出了一种新的一锅式硝化方法，该方法采用硝酸四甲基铵和三氟甲磺酸酐在二氯甲烷中的溶液，以提供易于使用的三氟甲磺酸硝化硝化剂的来源。实现了多种芳香族和杂芳香族底物的快速选择性硝化，从而合成了几种新型有机化合物。一个明显的优点是通过水后处理除去不需要的副产物。这种非常温和的硝化作用可实现大规模合成，并获得较高的分离产物收率，而通常无需进一步纯化。这种基于硝酸四甲基铵的硝化也已应用于微波辅助条件，并概述了几种化合物的结果。