Biaryl compounds with axial chirality are very common in synthetic chemistry, especially in catalysis. Axially chiral biaryls are important due to their biological activities and extensive applications in asymmetric catalysis. Thus the development of efficient enantioselective methods for their synthesis has attracted considerable attention. This Minireview discusses the progress made in catalytic kinetic resolution of biaryl compounds and chronicles significant advances made recently in catalytic kinetic resolution of biaryl scaffolds.

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联芳基化合物的催化动力学拆分

具有轴向手性的联芳基化合物在合成化学中非常常见，尤其是在催化中。轴向手性联芳基由于其生物活性和在不对称催化中的广泛应用而很重要。因此，开发用于其合成的有效对映选择性方法引起了相当大的关注。这份Minireview讨论了联芳基化合物的催化动力学拆分方面的进展，并记载了联芳基支架的催化动力学拆分方面最近取得的重大进展。