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N,O-Bis(trifluoroacetyl)hydroxylamine as a useful electrophilic nitrogen source: catalytic synthesis of N-(trifluoroacetyl)sulfilimines.
Organic Letters ( IF 4.9 ) Pub Date : 1999 Jul 15
Tomooka, C S, LeCloux, D D, Sasaki, H, Carreira, E M

[formula: see text] In the presence of catalytic quantites of Cu(OTf)2 the novel hydroxamic acid anhydride salt functions competently in the trifluoroacetamidation of sulfides to afford N-(trifluoroacetyl)sulfilimines. The salient features of this salt include its ease of synthesis from the inexpensive, commercially available starting materials trifluoroacetic anhydride and hydroxylamine hydrochloride.

中文翻译:

N,O-双(三氟乙酰基)羟胺可用作有用的亲电子氮源:N-(三氟乙酰基)亚磺胺的催化合成。

在Cu(OTf)2的催化量存在下,新型异羟肟酸酐盐在硫化物的三氟乙酰胺化中有效地起作用,以提供N-(三氟乙酰基)亚磺酰亚胺。该盐的显着特征包括易于从廉价的市售起始原料三氟乙酸酐和盐酸羟胺合成。
更新日期:2017-01-31
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