Vertebrate Bitter Taste Receptors: Keys for Survival in Changing Environments,Journal of Agricultural and Food Chemistry

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Vertebrate Bitter Taste Receptors: Keys for Survival in Changing Environments
Journal of Agricultural and Food Chemistry ( IF 5.7 ) Pub Date : 2016-12-25 00:00:00 , DOI: 10.1021/acs.jafc.6b04835
Maik Behrens ₁ , Wolfgang Meyerhof ₁

Affiliation

Research on bitter taste receptors has made enormous progress during recent years. Although in the early period after the discovery of this highly interesting receptor family special emphasis was placed on the deorphanization of mainly human bitter taste receptors, the research focus has shifted to sophisticated structure–function analyses, the discovery of small-molecule interactors, and the pharmacological profiling of nonhuman bitter taste receptors. These findings allowed novel perspectives on, for example, evolutionary and ecological questions that have arisen and that are discussed.

中文翻译：

脊椎苦味觉受体：在不断变化的环境中生存的关键

近年来，苦味受体的研究取得了巨大进展。尽管在发现这种高度有趣的受体家族后的初期，人们特别着重于主要是人类苦味受体的脱孤儿化，但研究重点已转移到复杂的结构-功能分析，小分子相互作用物的发现以及非人类苦味受体的药理分析。这些发现使人们对例如已出现并已讨论的进化和生态问题提出了新颖的见解。

更新日期：2016-12-25

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