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Advanced Photoacoustic Imaging Applications of Near‐Infrared Absorbing Organic Nanoparticles
Small ( IF 13.0 ) Pub Date : 2017-06-08 , DOI: 10.1002/smll.201700710 Yuyan Jiang 1 , Kanyi Pu 1
Small ( IF 13.0 ) Pub Date : 2017-06-08 , DOI: 10.1002/smll.201700710 Yuyan Jiang 1 , Kanyi Pu 1
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Progress of nanotechnology in recent years has stimulated fast development of nanoparticles in biomedical research. Photoacoustic (PA) imaging as an emerging non‐invasive technique in molecular imaging has improved imaging depth relative to conventional optical imaging, demonstrating great potential in clinical applications. The convergence of nanotechnology and PA imaging has enabled a broad spectrum of new opportunities in fundamental biology and translation medicine. This review focuses on the recent advances of organic nanoparticles in PA imaging applications. Near‐infrared absorbing organic nanoparticles are classified and discussed according to their different imaging applications, which include tumor imaging, gastrointestinal imaging, sentinel lymph node imaging, disease microenvironment imaging and real‐time drug imaging. The chemistry and PA properties of organic nanoparticles are discussed in details to highlight their own merits, and their challenges and perspectives in PA imaging are also discussed.
中文翻译：
近红外吸收有机纳米粒子的先进光声成像应用
近年来，纳米技术的进步刺激了生物医学研究中纳米颗粒的快速发展。与传统的光学成像相比，光声（PA）成像作为分子成像中一种新兴的非侵入性技术，具有更高的成像深度，在临床应用中显示出巨大的潜力。纳米技术和PA成像技术的融合为基础生物学和翻译医学带来了广泛的新机遇。这篇综述集中在有机纳米粒子在PA成像应用中的最新进展。根据近红外吸收性有机纳米颗粒的不同成像应用进行分类和讨论，包括肿瘤成像，胃肠道成像，前哨淋巴结成像，疾病微环境成像和实时药物成像。
更新日期：2017-06-08
中文翻译：
近红外吸收有机纳米粒子的先进光声成像应用
近年来，纳米技术的进步刺激了生物医学研究中纳米颗粒的快速发展。与传统的光学成像相比，光声（PA）成像作为分子成像中一种新兴的非侵入性技术，具有更高的成像深度，在临床应用中显示出巨大的潜力。纳米技术和PA成像技术的融合为基础生物学和翻译医学带来了广泛的新机遇。这篇综述集中在有机纳米粒子在PA成像应用中的最新进展。根据近红外吸收性有机纳米颗粒的不同成像应用进行分类和讨论，包括肿瘤成像，胃肠道成像，前哨淋巴结成像，疾病微环境成像和实时药物成像。
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