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熵力通过SNARE蛋白驱动自组织和膜融合[生物物理学和计算生物学]
Proceedings of the National Academy of Sciences of the United States of America ( IF 9.4 ) Pub Date : 2017-05-23 12:19:04 , DOI: 10.1073/pnas.1611506114 Hakhamanesh Mostafavi 1 , Sathish Thiyagarajan 2 , Benjamin S. Stratton 1 , Erdem Karatekin 3, 4, 5 , Jason M. Warner 1 , James E. Rothman 4, 6 , Ben O’Shaughnessy 1
Proceedings of the National Academy of Sciences of the United States of America ( IF 9.4 ) Pub Date : 2017-05-23 12:19:04 , DOI: 10.1073/pnas.1611506114 Hakhamanesh Mostafavi 1 , Sathish Thiyagarajan 2 , Benjamin S. Stratton 1 , Erdem Karatekin 3, 4, 5 , Jason M. Warner 1 , James E. Rothman 4, 6 , Ben O’Shaughnessy 1
Affiliation
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SNARE蛋白是细胞融合机制的核心，几乎可以介导胞吐作用和运输所依赖的所有已知细胞内膜融合反应。当囊泡相关的v-SNARE与靶膜相关的t-SNARE形成反式-SNARE复合物（“ SNAREpins”）时，融合被催化，每个SNAREpin的拉链状过程释放约65 kT。融合需要几个...
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更新日期：2017-05-24
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