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(-)-6-Chloro-2-[(1-furo[2, 3-c]pyridin-5-ylethyl)thio]-4-pyrimidinamine, PNU-142721, a new broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitor.
Journal of Medicinal Chemistry ( IF 6.8 ) Pub Date : 1998 Apr 23 , DOI: 10.1021/jm9801049 Donn G. Wishka 1 , David R. Graber 1 , Laurice A. Kopta 1 , Robert A. Olmsted 1 , Janice M. Friis 1 , John D. Hosley 1 , Wade J. Adams 1 , Eric P. Seest 1 , Thomas M. Castle 1 , Lester A. Dolak 1 , Barbara J. Keiser 1 , Yoshihiko Yagi 1 , Azhwarsamy Jeganathan 1 , Stephen T. Schlachter 1 , Michael J. Murphy 1 , Gary J. Cleek 1 , Richard A. Nugent 1 , Susan M. Poppe 1 , Steven M. Swaney 1 , Fusen Han 1 , William Watt 1 , Wendy L. White 1 , Toni-Jo Poel 1 , Richard C. Thomas 1 , Richard L. Voorman 1 , Kevin J. Stefanski 1 , Randall G. Stehle 1 , W. Gary Tarpley 1 , Joel Morris 1
中文翻译:
(-)-6-氯-2-[((1-呋喃[2,3-c]吡啶-5-基乙基)硫基] -4-嘧啶胺,PNU-142721,一种新的广谱HIV-1非核苷反向化合物转录酶抑制剂。
更新日期:2017-01-31
Journal of Medicinal Chemistry ( IF 6.8 ) Pub Date : 1998 Apr 23 , DOI: 10.1021/jm9801049 Donn G. Wishka 1 , David R. Graber 1 , Laurice A. Kopta 1 , Robert A. Olmsted 1 , Janice M. Friis 1 , John D. Hosley 1 , Wade J. Adams 1 , Eric P. Seest 1 , Thomas M. Castle 1 , Lester A. Dolak 1 , Barbara J. Keiser 1 , Yoshihiko Yagi 1 , Azhwarsamy Jeganathan 1 , Stephen T. Schlachter 1 , Michael J. Murphy 1 , Gary J. Cleek 1 , Richard A. Nugent 1 , Susan M. Poppe 1 , Steven M. Swaney 1 , Fusen Han 1 , William Watt 1 , Wendy L. White 1 , Toni-Jo Poel 1 , Richard C. Thomas 1 , Richard L. Voorman 1 , Kevin J. Stefanski 1 , Randall G. Stehle 1 , W. Gary Tarpley 1 , Joel Morris 1
Affiliation
中文翻译:
(-)-6-氯-2-[((1-呋喃[2,3-c]吡啶-5-基乙基)硫基] -4-嘧啶胺,PNU-142721,一种新的广谱HIV-1非核苷反向化合物转录酶抑制剂。