7 alpha-, 12 alpha-, 12 beta-Hydroxy and 7 alpha,12 alpha- and 7 alpha,12 beta-dihydroxy-3-ketocholanoic acids were prepared in satisfactory yields protecting the 3-keto group as dimethyl ketal and subsequent reduction with sodium borohydride of the corresponding 7- and 12-oxo functionalities. The same procedure gave also 3,12-diketo-7 alpha-hydroxy-cholanoic acid.

中文翻译：

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通过还原3,7-，3,12-和3,7,12-氧代衍生物合成7-和12-羟基-羟基和7,12-二羟基-3-酮基5β-cholan-24-oic酸。

以令人满意的产率制备了7个α-，12个α-，12个β-羟基和7个α，12个α-和7个α，12个β-二羟基-3-酮胆酸，保护了3-酮基作为二甲基缩酮，随后用相应的7-和12-氧代官能团的硼氢化钠。相同的方法也得到3，12-二酮-7α-羟基-胆酸。