A water soluble binaphthyl-based aldehyde was designed and synthesized. This compound in combination with Zn(OAc)₂ is found to exhibit greatly enhanced fluorescence in the presence of GSH in aqueous solution (pH=7.5) but give little or no fluorescence enhancement in the presence of cysteine, homocysteine and other amino acids. This remarkable selectivity makes this probe potentially useful for the analysis of the biologically important GSH.

中文翻译：

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水溶性联萘醛对谷胱甘肽的高度选择性荧光识别

设计并合成了水溶性联萘基醛。发现该化合物与Zn（OAc）_2的组合在水溶液中存在GSH（pH = 7.5）时显示出大大增强的荧光，但是在半胱氨酸，高半胱氨酸和其他氨基酸的存在下几乎没有或没有荧光增强。这种非凡的选择性使该探针可能对生物学上重要的GSH的分析有用。