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Bimane: A Visible Light Induced Fluorescent Photoremovable Protecting Group for the Single and Dual Release of Carboxylic and Amino Acids
Organic Letters ( IF 4.9 ) Pub Date : 2017-03-10 00:00:00 , DOI: 10.1021/acs.orglett.7b00416
Amrita Chaudhuri 1 , Yarra Venkatesh 1 , Krishna Kalyani Behara 1 , N. D. Pradeep Singh 1
Affiliation  

A series of ester conjugates of carboxylic and amino acids were synthesized based on bimane fluorescent photoremovable protecting group (FPRPG). The photorelease of single and dual (same as well as different) carboxylic and amino acids is demonstrated from a single bimane molecule on irradiation with visible light (λ ≥ 410 nm). The detailed mechanistic study of photorelease revealed that the release of two caged acids is simultaneous but in a stepwise pathway.

中文翻译:

Bimane:可见光诱导的荧光光可去除保护基团,用于羧基和氨基酸的单和双释放

基于二元荧光可光脱保护基(FPRPG),合成了一系列羧酸和氨基酸的酯共轭物。在可见光(λ≥410 nm)照射下,一个单一的双烯类分子证明了单个和双重(相同以及不同)羧基和氨基酸的光释放。光释放的详细机理研究表明,两种笼形酸的释放是同时的,但是是逐步的。
更新日期:2017-03-10
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