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Synthesis of hydroxyl-functionalized N-heterocyclic carbene gold(i) complexes and peptide conjugates†
Dalton Transactions ( IF 3.5 ) Pub Date : 2017-02-09 00:00:00 , DOI: 10.1039/c6dt04834j
Tobias Diehl 1, 2, 3 , Melanie T. S. Krause 1, 2, 3 , Sven Ueberlein 1, 2, 3 , Stefanie Becker 1, 2, 3 , Aline Trommer 1, 2, 3 , Gregor Schnakenburg 1, 2, 3 , Marianne Engeser 1, 2, 3
Dalton Transactions ( IF 3.5 ) Pub Date : 2017-02-09 00:00:00 , DOI: 10.1039/c6dt04834j
Tobias Diehl 1, 2, 3 , Melanie T. S. Krause 1, 2, 3 , Sven Ueberlein 1, 2, 3 , Stefanie Becker 1, 2, 3 , Aline Trommer 1, 2, 3 , Gregor Schnakenburg 1, 2, 3 , Marianne Engeser 1, 2, 3
Affiliation
The synthesis and characterization of a series of new cationic gold(I) complexes with hydroxyl-functionalized N-heterocyclic carbene (NHC) ligands is described. They are valuable building blocks for further derivatization: as a first example, coupling with amino acids and a dipeptide, respectively, successfully results in amino acid and peptide conjugates that are hard to obtain by other synthetic routes.
中文翻译:
羟基官能化的N-杂环卡宾金(i)配合物和肽结合物的合成†
描述了具有羟基官能化的N-杂环卡宾(NHC)配体的一系列新型阳离子金(I)配合物的合成和表征。它们是进一步衍生化的有价值的组成部分:作为第一个例子,分别与氨基酸和二肽偶联,可成功产生难以通过其他合成途径获得的氨基酸和肽结合物。
更新日期:2017-02-09
中文翻译:

羟基官能化的N-杂环卡宾金(i)配合物和肽结合物的合成†
描述了具有羟基官能化的N-杂环卡宾(NHC)配体的一系列新型阳离子金(I)配合物的合成和表征。它们是进一步衍生化的有价值的组成部分:作为第一个例子,分别与氨基酸和二肽偶联,可成功产生难以通过其他合成途径获得的氨基酸和肽结合物。