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Integrating Oxaliplatin with Highly Luminescent Carbon Dots: An Unprecedented Theranostic Agent for Personalized Medicine
Advanced Materials ( IF 27.4 ) Pub Date : 2014-03-14 , DOI: 10.1002/adma.201306192
Min Zheng 1 , Shi Liu 2, 3 , Jing Li 2 , Dan Qu 1, 3 , Haifeng Zhao 1 , Xingang Guan 2 , Xiuli Hu 2 , Zhigang Xie 2 , Xiabin Jing 2 , Zaicheng Sun 1
Advanced Materials ( IF 27.4 ) Pub Date : 2014-03-14 , DOI: 10.1002/adma.201306192
Min Zheng 1 , Shi Liu 2, 3 , Jing Li 2 , Dan Qu 1, 3 , Haifeng Zhao 1 , Xingang Guan 2 , Xiuli Hu 2 , Zhigang Xie 2 , Xiabin Jing 2 , Zaicheng Sun 1
Affiliation
A theranostic nanomedicine (CD‐Oxa) is synthesized by means of the condensation reaction between the amino groups on the surface of fluorescent carbon dots (CDs) and the carboxyl group of the oxaliplatin derivative Oxa(IV)‐COOH. CD‐Oxa, which integrates the optical properties of CDs and the anticancer function of oxaliplatin, could be used for simultaneous drug delivery and fluorescent tracking.
中文翻译:
奥沙利铂与高发光碳点的整合:前所未有的个性化药物治疗药物
通过荧光碳点(CDs)表面的氨基与奥沙利铂衍生物Oxa(IV)-COOH的羧基之间的缩合反应合成了治疗性纳米药物(CD-Oxa)。CD‐Oxa整合了CD的光学特性和奥沙利铂的抗癌功能,可用于同时给药和荧光跟踪。
更新日期:2014-03-14

中文翻译:

奥沙利铂与高发光碳点的整合:前所未有的个性化药物治疗药物
通过荧光碳点(CDs)表面的氨基与奥沙利铂衍生物Oxa(IV)-COOH的羧基之间的缩合反应合成了治疗性纳米药物(CD-Oxa)。CD‐Oxa整合了CD的光学特性和奥沙利铂的抗癌功能,可用于同时给药和荧光跟踪。
