Visible-Light-Induced C2 Alkylation of Pyridine N-Oxides,The Journal of Organic Chemistry

当前位置： X-MOL 学术 › J. Org. Chem. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Visible-Light-Induced C2 Alkylation of Pyridine N-Oxides
The Journal of Organic Chemistry ( IF 3.3 ) Pub Date : 2017-02-01 00:00:00 , DOI: 10.1021/acs.joc.6b02891
Wen-Man Zhang ₁ , Jian-Jun Dai ₁ , Jun Xu ₁ , Hua-Jian Xu ₁

Affiliation

A photoredox catalytic method has been developed for the direct C2 alkylation of pyridine N-oxides. This reaction is compatible with a range of synthetically relevant functional groups for providing efficient synthesis of a variety of C2-alkylated pyridine N-oxides under mild conditions. Mechanistic studies are consistent with the generation of a radical intermediate along the reaction pathway.

中文翻译：