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A Bioorthogonal Raman Reporter Strategy for SERS Detection of Glycans on Live Cells
Angewandte Chemie International Edition ( IF 16.1 ) Pub Date : 2013-05-23 , DOI: 10.1002/anie.201301387
Liang Lin 1 , Xiangdong Tian 2 , Senlian Hong 3 , Peng Dai 1 , Qiancheng You 1 , Ruyi Wang 1 , Lianshun Feng 1 , Can Xie 3 , Zhong‐Qun Tian 2 , Xing Chen 1
Affiliation  

Direct detection of glycans on live cells using surface‐enhanced Raman scattering (SERS) has been shown. A bioorthogonal Raman reporter was directly installed onto the monosaccharide analogs. Once metabolically incorporated into cell surface glycans, the Raman reporter was detected using SERS (see picture).
image


中文翻译:

SERS检测活细胞上的聚糖的生物正交拉曼报道策略

使用表面增强拉曼散射(SERS)可以直接检测活细胞上的聚糖。将生物正交拉曼报道分子直接安装在单糖类似物上。一旦代谢整合到细胞表面聚糖中,就可以使用SERS检测拉曼报告基因(参见图片)。
图像
更新日期:2013-05-23
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