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Asymmetric Epoxidation of Conjugated Olefins with Dioxygen
Angewandte Chemie International Edition ( IF 16.1 ) Pub Date : 2012-07-23 , DOI: 10.1002/anie.201201848
Shota Koya , Yota Nishioka , Hirotaka Mizoguchi , Tatsuya Uchida , Tsutomu Katsuki

A complex situation: Asymmetric epoxidation of conjugated olefins was achieved at room temperature using ruthenium complex 1 as the catalyst and air as the oxidant to give epoxides in up to 95 % ee (see scheme). When the product was acid sensitive, the reaction was carried out at 0 °C under oxygen.
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中文翻译:

共轭烯烃与双氧的不对称环氧化

复杂的情况:使用钌配合物1作为催化剂,空气作为氧化剂,在室温下实现了共轭烯烃的不对称环氧化,生成的环氧化物含量高达95%  ee(参见方案)。当产物对酸敏感时,反应在0℃在氧气下进行。
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更新日期:2012-07-23
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