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Synthesis of gem‐Difluorinated Cyclopropanes and Cyclopropenes: Trifluoromethyltrimethylsilane as a Difluorocarbene Source
Angewandte Chemie International Edition ( IF 16.1 ) Pub Date : 2011-06-16 , DOI: 10.1002/anie.201101691
Fei Wang , Tao Luo , Jinbo Hu , Ying Wang , Hema S. Krishnan , Parag V. Jog , Somesh K. Ganesh , G. K. Surya Prakash , George A. Olah

Highly versatile: The Ruppert–Prakash reagent (Me3SiCF3) can be an efficient source of difluorocarbene. By varying the nonmetallic initiator that is used (F at lower temperatures and I at higher temperatures), a range of structurally diverse alkenes and alkynes can be converted into the corresponding gem‐difluorinated cyclopropanes and cyclopropenes in good yields (see scheme).
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中文翻译:

宝石二氟环丙烷和环丙烯的合成:以三氟甲基三甲基硅烷为二氟卡宾来源

用途广泛:Ruppert–Prakash试剂(Me 3 SiCF 3)可以是二氟卡宾的有效来源。通过改变所使用的非金属引发剂(F -在较低温度和我-在更高的温度),范围结构多样的烯烃和炔烃的可转化成相应的宝石-difluorinated以良好产率和环丙烷环丙烯(参见方案)。
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更新日期:2011-06-16
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