The clinical application of cell‐based therapy is severely hampered by restricted cell survival and poor understanding of cell fate after transplantation. C. Shi and co‐workers describe a novel near‐infrared mitochondria‐targeting heptamethine dye (NIRCP‐61) on page 8397, developed to simultaneously enable cell tracking and cytoprotection in cytotherapy. This small‐molecule fluorophore maintains superior fluorescent imaging properties while inducing cytoprotective effects against oxidative stress to augment tissue repair and regeneration.

中文翻译：

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组织修复：用于细胞移植的治疗性小分子荧光团的开发（Adv。Funct。Mater。46/2016）

由于细胞存活受限，且移植后对细胞命运的了解不足，严重阻碍了基于细胞疗法的临床应用。C. Shi和他的同事们在第8397页上描述了一种新型的近红外线粒体靶向七甲胺染料（NIRCP-61），该染料可同时在细胞疗法中实现细胞跟踪和细胞保护。这种小分子荧光团可保持出色的荧光成像性能，同时诱导针对氧化应激的细胞保护作用，从而增强组织修复和再生能力。