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Asymmetric Ketone Reduction by Imine Reductases
ChemBioChem ( IF 2.6 ) Pub Date : 2016-12-30 , DOI: 10.1002/cbic.201600647
Maike Lenz 1 , Jan Meisner 2 , Leann Quertinmont 3 , Stefan Lutz 3 , Johannes Kästner 2 , Bettina M. Nestl 1
Affiliation  

IRED vs. KRED: Asymmetric reduction of a highly reactive carbonyl compound has been accomplished with an imine reductase. Kinetics and in silico studies have yielded mechanistic insights, thus allowing an understanding of this promiscuous behaviour.
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中文翻译:

亚胺还原酶的不对称酮还原

IRED与KRED的比较:高反应性羰基化合物的不对称还原是通过亚胺还原酶完成的。动力学和计算机模拟研究产生了机械方面的见解,因此可以理解这种混杂行为。
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更新日期:2016-12-30
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