Tetraphenylethene-based highly emissive metallacage as a component of theranostic supramolecular nanoparticles [Biochemistry],Proceedings of the National Academy of Sciences of the United States of America

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Tetraphenylethene-based highly emissive metallacage as a component of theranostic supramolecular nanoparticles [Biochemistry]
Proceedings of the National Academy of Sciences of the United States of America ( IF 9.4 ) Pub Date : 2016-11-29 08:48:07 , DOI: 10.1073/pnas.1616836113
Guocan Yu ₁ , Timothy R. Cook ₂ , Yang Li ₃ , Xuzhou Yan ₄ , Dan Wu ₃ , Li Shao ₁ , Jie Shen ₃ , Guping Tang ₃ , Feihe Huang ₁ , Xiaoyuan Chen ₅ , Peter J. Stang ₄

Affiliation

A theranostic agent combines diagnostic reporter with therapeutic activity in a single entity, an approach that seeks to increase the efficacy of cancer treatment. Herein, we describe the synthesis of a highly emissive tetraphenylethene-based metallacage using multicomponent coordination-driven self-assembly that exhibits a coordination-triggered aggregation-induced emission (AIE) enhancement. The formation of...

中文翻译：

基于四苯乙烯的高发射金属笼罩作为治疗型超分子纳米颗粒的组成部分[生物化学]

治疗试剂将诊断报告基因与治疗活性结合在一个实体中，该方法旨在提高癌症治疗的效力。在这里，我们描述了使用多组分配位驱动的自组装，展示了配位触发的聚集诱导的发射（AIE）增强的高发射四苯乙烯基金属绷带的合成。的形成...

更新日期：2016-12-01

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