Streptomyces sp. strain GoM1 was found to produce seven novel glycosides (2–8) containing the rare deoxysugar 6-deoxy-α-L-talose. The aglycones are small phenols, isovaleric acid or aromatic carboxylic acids. By precursor-directed biosynthesis, the yields of the compounds could be increased significantly. Feeding of 4-hydroxybenzoic acid led to the production of both acyl and aryl glycosides, and of compound 9 with both structural elements. Pyrrol-2-ylcarbonyl 6-deoxy-α-L-talopyranoside (6) shows remarkable growth inhibition of some parasites. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)

中文翻译：

---

来自 Streptomyces sp. 的 6-Deoxy-α-L-talopyranosides。

链霉菌属 发现菌株 GoM1 产生七种新型糖苷 (2-8)，其中包含稀有的脱氧糖 6-脱氧-α-L-塔糖。苷元是小酚、异戊酸或芳香羧酸。通过前体导向的生物合成，可以显着提高化合物的产量。4-羟基苯甲酸的进料导致产生酰基和芳基糖苷，以及具有两种结构元素的化合物9。Pyrrol-2-ylcarbonyl 6-deoxy-α-L-talopyranoside (6) 对某些寄生虫具有显着的生长抑制作用。(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)