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An Overview of Syntheses of Apogalanthamine Analogues and 7-Aza Derivatives of Steganacin and Steganone
European Journal of Organic Chemistry ( IF 2.5 ) Pub Date : 2008-12-01 , DOI: 10.1002/ejoc.200800699 Prasad Appukkuttan , Erik Van der Eycken
European Journal of Organic Chemistry ( IF 2.5 ) Pub Date : 2008-12-01 , DOI: 10.1002/ejoc.200800699 Prasad Appukkuttan , Erik Van der Eycken
A concise and critical overview of the developments in the synthesis of apogalanthamine analogues and steganacin and steganone 7-aza analogues over the last four decades is presented. These amaryllidaceae alkaloid analogues bear a 5,6,7,8-tetrahydrodibenz[c,e]azocine skeleton, and are well known for their diverse and potent biological activities. This microreview will briefly glance over the history and early developments in the field at the beginning, and will, in the latter parts, concentrate on the recent synthetic developments in the synthesis of the title molecules. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
中文翻译:
Apogalanthamine 类似物和 Steganacin 和 Steganone 的 7-Aza 衍生物的合成概述
介绍了过去四十年中阿朴加兰他敏类似物和 steganacin 和 steganone 7-aza 类似物的合成发展的简明而重要的概述。这些石蒜科生物碱类似物具有 5,6,7,8-四氢二苯并[c,e]azocine 骨架,并以其多样化和有效的生物活性而闻名。这篇微观评论将在开头简要回顾该领域的历史和早期发展,并将在后面的部分集中讨论标题分子合成的近期合成发展。(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
更新日期:2008-12-01
中文翻译:
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Apogalanthamine 类似物和 Steganacin 和 Steganone 的 7-Aza 衍生物的合成概述
介绍了过去四十年中阿朴加兰他敏类似物和 steganacin 和 steganone 7-aza 类似物的合成发展的简明而重要的概述。这些石蒜科生物碱类似物具有 5,6,7,8-四氢二苯并[c,e]azocine 骨架,并以其多样化和有效的生物活性而闻名。这篇微观评论将在开头简要回顾该领域的历史和早期发展,并将在后面的部分集中讨论标题分子合成的近期合成发展。(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)