We report herein the synthesis and applications of 1-(trifluoromethyl)cyclopent-3-ene-1-carboxylic acid and itsesters, promising new trifluoromethylated cyclic building blocks. Initially prepared starting from a pentafluorodithiopropanoic ester, a more convenient and effective approach has been developed starting from commercially available trifluoropropanoic acid or its methyl ester. The interest in these building blocks is exemplified by their use as platforms for a variety of difunctional trifluoromethylcyclopentane derivatives.

中文翻译：

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1-（三氟甲基）环戊-3-烯羧酸衍生物：双功能环状三氟甲基结构单元的平台

我们在此报告了 1-（三氟甲基）环戊-3-烯-1-羧酸及其酯的合成和应用，有望成为新的三氟甲基化环状结构单元。最初从五氟二硫代丙酸酯开始制备，从市售的三氟丙酸或其甲酯开始开发了一种更方便和有效的方法。对这些构件的兴趣体现在它们用作各种双官能三氟甲基环戊烷衍生物的平台。