当前位置:
X-MOL 学术
›
Med. Sci. Sports Exercise
›
论文详情
Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
Effects of Resistance Training on Muscular Adaptations and Inflammatory Markers in Overweight and Obese Men.
Medicine & Science in Sports & Exercise ( IF 4.1 ) Pub Date : 2024-11-15 , DOI: 10.1249/mss.0000000000003592
Navid Bagheri,Reza Bagheri,Jakub Mesinovic,Hamid Ghobadi,David Scott,Mehdi Kargarfard,Fred Dutheil
Medicine & Science in Sports & Exercise ( IF 4.1 ) Pub Date : 2024-11-15 , DOI: 10.1249/mss.0000000000003592
Navid Bagheri,Reza Bagheri,Jakub Mesinovic,Hamid Ghobadi,David Scott,Mehdi Kargarfard,Fred Dutheil
Purpose: Obesity may blunt exercise responsiveness to improve muscular adaptations. The effect of resistance training (RT) targeting different body regions on muscle and inflammatory markers is unclear. This study aimed to investigate the impact of upper (upper body exercises), lower (lower body exercises), or combined (upper body + lower body exercises) RT on muscle and inflammatory markers, body composition, and performance in overweight and obese men.Methods: Sixty overweight and obese men (age = 31 ± 4 years) were randomly assigned to one of 4 groups: upper-body RT (UB; n = 15), lower-body RT (LB; n = 15), combined RT (UB + LB; n = 15) or control (C; n = 15). The training protocol consisted of 3 exercise sessions per week for 12 weeks. Blood samples for measuring serum markers (follistatin, myostatin, C-reactive protein [CRP], adiponectin, tumor necrosis factor-α [TNF-α], and irisin) were obtained at baseline and 48 hours after the final training session. Fat mass (FM), body fat percentage (BFP), skeletal muscle mass (SMM), and fat-free mass (FFM) were measured using bioelectrical impedance analysis (Inbody 720).Results: SMM, FFM, UB and LB strength and power, follistatin, follistatin:myostatin ratio, adiponectin, and irisin significantly increased while FM, BFP, myostatin, CRP, and TNF-α significantly reduced from pre- to post-training in all training groups (p < 0.05). Changes in LB muscle power (r = 0.558), both UB (r = 0.518) and LB (r = 0.419) muscle strength, and follistatin (r = 0.545), had moderate positive relationships with ΔSMM, while changes in myostatin (r = -0.585) had a moderate negative relationship with ΔSMM. Also, changes in myostatin (r = 0.825) and CRP (r = 0.715) had a strong positive relationship with ΔFM, while TNF-α (r = 0.467) had a moderate positive relationship with ΔFM. Follistatin (r = -0.789) and adiponectin (r = -0.713) had a strong negative relationship with ΔFM, while irisin (r = -0.426) had a moderate negative relationship with ΔFM.Conclusions: Combined RT elicits the greatest increases in follistatin, follistatin:myostatin ratio, adiponectin, and decreases in myostatin and CRP compared with other training groups in overweight and obese men. However, systemic improvements may be achieved through performing UB or LB RT alone.
中文翻译:
阻力训练对超重和肥胖男性肌肉适应和炎症标志物的影响。
目的:肥胖可能会减弱运动反应性,从而改善肌肉适应能力。针对不同身体区域的阻力训练 (RT) 对肌肉和炎症标志物的影响尚不清楚。本研究旨在调查上半身 (上半身运动)、下半身 (下半身运动) 或联合 (上半身 + 下半身运动) RT 对超重和肥胖男性肌肉和炎症标志物、身体成分和表现的影响。方法:将 60 名超重和肥胖男性 (年龄 = 31 ± 4 岁) 随机分配到 4 组中的一组:上半身 RT (UB;n = 15)、下半身 RT (LB;n = 15)、联合 RT (UB + LB;n = 15) 或对照组 (C;n = 15)。训练方案包括每周 3 次锻炼,持续 12 周。在基线和最后一次训练后 48 小时采集用于测量血清标志物(卵泡抑素、肌肉生长抑制素、C 反应蛋白 [CRP]、脂联素、肿瘤坏死因子-α [TNF-α] 和鸢尾素)的血样。使用生物电阻抗分析 (Inbody 720) 测量脂肪量 (FM)、体脂百分比 (BFP)、骨骼肌量 (SMM) 和无脂肪量 (FFM)。结果: 所有训练组的 SMM、FFM、UB 和 LB 强度和爆发力、卵泡抑素、卵泡抑素:肌肉生长抑制素比率、脂联素和鸢尾素显着增加,而 FM、BFP、肌肉生长抑制素、CRP 和 TNF-α 显著降低 (p < 0.05)。LB 肌肉力量 (r = 0.558)、UB (r = 0.518) 和 LB (r = 0.419) 肌肉力量以及卵泡抑素 (r = 0.545) 的变化与 ΔSMM 呈中度正相关,而肌肉生长抑制素 (r = -0.585) 的变化与 ΔSMM 呈中度负相关。此外,肌肉生长抑制素 (r = 0.825) 和 CRP (r = 0.715) 的变化与 ΔFM 有很强的正相关,而 TNF-α (r = 0.467) 与 ΔFM 呈中度正相关。卵泡抑素 (r = -0.789) 和脂联素 (r = -0.713) 与 ΔFM 呈强负相关,而鸢尾素 (r = -0.426) 与 ΔFM 呈中度负相关结论:与其他训练组相比,联合放疗在超重和肥胖男性中引起卵泡抑素、卵泡抑素:肌肉生长抑制素比值、脂联素以及肌肉生长抑制素和 CRP 的降低最大增加。然而,仅进行 UB 或 LB RT 可实现全身改善。
更新日期:2024-11-15
中文翻译:
![](https://scdn.x-mol.com/jcss/images/paperTranslation.png)
阻力训练对超重和肥胖男性肌肉适应和炎症标志物的影响。
目的:肥胖可能会减弱运动反应性,从而改善肌肉适应能力。针对不同身体区域的阻力训练 (RT) 对肌肉和炎症标志物的影响尚不清楚。本研究旨在调查上半身 (上半身运动)、下半身 (下半身运动) 或联合 (上半身 + 下半身运动) RT 对超重和肥胖男性肌肉和炎症标志物、身体成分和表现的影响。方法:将 60 名超重和肥胖男性 (年龄 = 31 ± 4 岁) 随机分配到 4 组中的一组:上半身 RT (UB;n = 15)、下半身 RT (LB;n = 15)、联合 RT (UB + LB;n = 15) 或对照组 (C;n = 15)。训练方案包括每周 3 次锻炼,持续 12 周。在基线和最后一次训练后 48 小时采集用于测量血清标志物(卵泡抑素、肌肉生长抑制素、C 反应蛋白 [CRP]、脂联素、肿瘤坏死因子-α [TNF-α] 和鸢尾素)的血样。使用生物电阻抗分析 (Inbody 720) 测量脂肪量 (FM)、体脂百分比 (BFP)、骨骼肌量 (SMM) 和无脂肪量 (FFM)。结果: 所有训练组的 SMM、FFM、UB 和 LB 强度和爆发力、卵泡抑素、卵泡抑素:肌肉生长抑制素比率、脂联素和鸢尾素显着增加,而 FM、BFP、肌肉生长抑制素、CRP 和 TNF-α 显著降低 (p < 0.05)。LB 肌肉力量 (r = 0.558)、UB (r = 0.518) 和 LB (r = 0.419) 肌肉力量以及卵泡抑素 (r = 0.545) 的变化与 ΔSMM 呈中度正相关,而肌肉生长抑制素 (r = -0.585) 的变化与 ΔSMM 呈中度负相关。此外,肌肉生长抑制素 (r = 0.825) 和 CRP (r = 0.715) 的变化与 ΔFM 有很强的正相关,而 TNF-α (r = 0.467) 与 ΔFM 呈中度正相关。卵泡抑素 (r = -0.789) 和脂联素 (r = -0.713) 与 ΔFM 呈强负相关,而鸢尾素 (r = -0.426) 与 ΔFM 呈中度负相关结论:与其他训练组相比,联合放疗在超重和肥胖男性中引起卵泡抑素、卵泡抑素:肌肉生长抑制素比值、脂联素以及肌肉生长抑制素和 CRP 的降低最大增加。然而,仅进行 UB 或 LB RT 可实现全身改善。