当前位置: X-MOL 学术Med. Sci. Sports Exercise › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Cigarette Smoking Impairs Cardiorespiratory and Metabolic Response at Peak Incremental Exercise and during Recovery in Young, Physically Active Adults.
Medicine & Science in Sports & Exercise ( IF 4.1 ) Pub Date : 2024-11-18 , DOI: 10.1249/mss.0000000000003602
Marta Borrelli,Christian Doria,Nicholas Toninelli,Stefano Longo,Giuseppe Coratella,Emiliano Cè,Susanna Rampichini,Fabio Esposito

Purpose: Cigarette smoking (CS) induces systemic changes that impair cardiorespiratory and muscular function both at rest and during exercise. Although these abnormalities are reported in sedentary, middle-aged smokers (SM) with pulmonary disease, few and controversial studies focused on young, physically active SM at the early stage of smoking history. This study aimed at assessing the impact CS on cardiorespiratory and metabolic response during an incremental test and the subsequent recovery in young, physically active SM without known lung or cardiovascular disease.Methods: After pulmonary function evaluation, 12 SM (age: 22±2 yr; body mass: 75±8 kg; stature: 1.78±0.06 m; 12±4 cigarette/day for 6±2 years; mean±SD) and 12 non-smokers (CTRL; age: 23±1 yr; body mass: 76±8 kg; stature: 1.79±0.08 m) matched for age and exercise habits, underwent an exhaustive incremental step test (25 W/2 min) on a cycle ergometer. Pulmonary O2 uptake (V'O2), expiratory ventilation (V'E), heart rate (fH) responses and lactate concentration were assessed during the test and subsequent recovery.Results: Despite similar static lung volumes, SM reported lower peak expiratory flow (-23%; P = 0.003) and maximal voluntary ventilation (-10%; P = 0.003). At submaximal exercise, no differences in the cardiorespiratory and metabolic were noted between the two groups. However, SM exhibited ventilatory (P < 0.01) and lactate thresholds at lower work rates (P = 0.01). At peak exercise, SM exhibited lower V'O2 (-8%; P = 0.02), mechanical power (-11%; P = 0.02) and V'E (-9%; P = 0.01). During recovery, SM showed longer time constants (τ) in V'O2 (+52%; P = 0.002), V'E (+19%; P = 0.027) and fH (+21%; P = 0.022) and smaller fH at 30 s of recovery (HRR30; -31%; P = 0.032).Conclusions: These results are compatible with an early CS-related impairment of the cardiorespiratory and metabolic function even in young individuals with relatively short smoking history.

中文翻译:


吸烟会损害年轻、身体活跃的成年人在增量运动高峰期和恢复期的心肺和代谢反应。



目的: 吸烟 (CS) 会诱发全身性变化,从而在休息和运动时损害心肺和肌肉功能。尽管这些异常在患有肺部疾病的久坐不动的中年吸烟者 (SM) 中有所报道,但很少有且有争议的研究集中在吸烟史早期的年轻、身体活跃的 SM 上。本研究旨在评估 CS 对增量测试期间心肺和代谢反应的影响,以及在没有已知肺部或心血管疾病的年轻、身体活跃的 SM 的后续恢复。方法:肺功能评估后,12 名 SM(年龄:22±2 岁;体重:75±8 kg;身材:1.78±0.06 m;12±4 支香烟/天,持续 6±2 岁;平均值±SD)和 12 名不吸烟者(CTRL;年龄:23±1 岁;体重:76±8 kg;身高:1.79±0.08 m)根据年龄和运动习惯匹配,在自行车测力计上进行了详尽的增量步数测试(25 W/2 min)。在测试和随后的恢复过程中评估肺 O2 摄取 (V'O2 )、呼气通气 (V'E) 、心率 (fH) 反应和乳酸浓度。结果: 尽管静态肺容量相似,但 SM 报告呼气峰流量较低 (-23%;P = 0.003)和最大自主通气量 (-10%;P = 0.003)。在次最大运动时,两组之间心肺和代谢没有差异。然而,SM 在较低的工作速率下表现出通气 (P < 0.01) 和乳酸阈值 (P = 0.01)。在运动高峰期,SM 表现出较低的 V'O2 (-8%;P = 0.02)、机械功率 (-11%;P = 0.02) 和 V'E (-9%;P = 0.01)。在恢复过程中,SM 在 V'O2 中显示出更长的时间常数 (τ) (+52%;P = 0.002)、V'E (+19%;P = 0.027) 和 fH (+21%;P = 0.022)和较小的 fH 在恢复 30 秒时 (HRR30; -31%;P = 0.032)。结论:这些结果与早期 CS 相关的心肺和代谢功能损害相符,即使在吸烟史相对较短的年轻人中也是如此。
更新日期:2024-11-18
down
wechat
bug