当前位置: X-MOL 学术Med. Sci. Sports Exercise › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Comparative Effects of Different Exercise Types on Cardiovascular Health and Executive Function in Sedentary Young Individuals.
Medicine & Science in Sports & Exercise ( IF 4.1 ) Pub Date : 2025-01-09 , DOI: 10.1249/mss.0000000000003645
Jinglin Huang,Lu Leng,Min Hu,Xuyan Cui,Xu Yan,Ziqing Liu,Kangle Wang,Jiarui Wu,Shan He,Weiji Deng,Peilun Li,Yilin Chen,Dongdong Gao,Yuan Wei,Junhao Huang

PURPOSE The present study aimed to compare the impacts of different exercise types on cardiovascular health and executive function in sedentary young individuals, and to determine the associations between cardiovascular function and executive function (EF) after exercise. METHODS Sixty-three sedentary participants were randomly divided into high-intensity interval training (HIIT), moderate-intensity continuous training (MICT), resistance exercise (RE), and control groups. Macro- and microvascular endothelial function were assessed using brachial artery flow-mediated dilation and fingertip reactive hyperemia index, respectively. Arterial stiffness was evaluated through carotid-femoral pulse wave velocity, ankle-brachial index, and augmentation index. EF performance was evaluated using the Stroop and N-back tasks. Functional near-infrared spectroscopy was employed to measure cortical activation and real-time oxyhemoglobin concentration (Oxy-Hb) changes in different cerebral regions. Key circulating biomarkers for vascular and cognitive function, including BDNF, irisin, VEGF, IGF-1, and TNF-α, were measured using enzyme-linked immunosorbent assays. RESULTS Eight weeks of HIIT, MICT, and RE effectively improved macro- and microvascular endothelial function while reducing arterial stiffness in sedentary young individuals. Furthermore, exercise-induced increase in BDNF level was correlated with enhanced macrovascular endothelial function, while increase in IGF-1 level was associated with enhanced microvascular endothelial function and reduced arterial stiffness. Notably, both HIIT and MICT, but not RE, efficiently enhanced Oxy-Hb level in certain brain regions, such as the FPA and DLPFC, leading to the improvement in EF performance. Exercise-induced increase in Oxy-Hb level and EF performance were correlated with enhanced BDNF level and endothelial function and reduced arterial stiffness. CONCLUSIONS Our study demonstrated that 8 weeks of HIIT, MICT, and RE effectively improved endothelial function in both macro- and microvessels, and arterial stiffness among sedentary young individuals. However, HIIT and MICT, but not RE, notably increased blood oxygen level in the FPA and DLPFC brain regions and improved EF performance. Due to the efficiency and time-saving features of HIIT, the present study highlights HIIT as an effective exercise prescription for promoting vascular and EF in sedentary young individuals. Importantly, the observed improvements in cardiovascular function following exercise training is pivotal in improving EF, and elevated circulating levels of biomarkers like BDNF and IGF-1, induced by exercise, are involved in the regulatory mechanisms.

中文翻译:


不同运动类型对久坐不动的年轻人心血管健康和执行功能的影响比较。



目的 本研究旨在比较不同运动类型对久坐不动的年轻人心血管健康和执行功能的影响,并确定运动后心血管功能与执行功能 (EF) 之间的关联。方法 将 63 例久坐不动的参与者随机分为高强度间歇训练 (HIIT) 、中等强度连续训练 (MICT) 、阻力运动 (RE) 和对照组。分别使用肱动脉血流介导的扩张和指尖反应性充血指数评估大血管和微血管内皮功能。通过颈股脉搏波速度、踝肱指数和增强指数评估动脉硬度。使用 Stroop 和 N-back 任务评估 EF 性能。采用功能性近红外光谱法测量不同大脑区域的皮质活化和实时氧合血红蛋白浓度 (Oxy-Hb) 变化。使用酶联免疫吸附测定法测量血管和认知功能的关键循环生物标志物,包括 BDNF 、 iriin 、 VEGF 、 IGF-1 和 TNF-α。结果 8 周的 HIIT 、 MICT 和 RE 有效改善了大血管和微血管内皮功能,同时减轻了久坐不动的年轻人的动脉僵硬。此外,运动诱导的 BDNF 水平升高与大血管内皮功能增强相关,而 IGF-1 水平升高与微血管内皮功能增强和动脉僵硬降低相关。值得注意的是,HIIT 和 MICT(而不是 RE)都有效地增强了某些大脑区域的 Oxy-Hb 水平,例如 FPA 和 DLPFC,从而提高了 EF 性能。 运动诱导的 Oxy-Hb 水平和 EF 性能增加与 BDNF 水平和内皮功能增强以及动脉僵硬降低相关。结论 我们的研究表明,8 周的 HIIT 、 MICT 和 RE 有效改善了久坐不动的年轻人的大血管和微血管的内皮功能以及动脉硬度。然而,HIIT 和 MICT,而不是 RE,显着增加了 FPA 和 DLPFC 脑区域的血氧水平并提高了 EF 表现。由于 HIIT 的效率和省时特性,本研究强调 HIIT 是促进久坐不动的年轻人血管和 EF 的有效运动处方。重要的是,运动训练后观察到的心血管功能改善对于改善 EF 至关重要,运动诱导的 BDNF 和 IGF-1 等生物标志物的循环水平升高与调节机制有关。
更新日期:2025-01-09
down
wechat
bug