Neuromuscular abnormality is the leading cause of disability in adults. Understanding the complex interplay between muscle structure and function is crucial for effective treatment and rehabilitation. However, the substantial deformation of muscles during movement (up to 40%) poses challenges for accurate assessment. To address this, we developed a wearable structural-functional sensing patch (WSFP) that enables synchronous analysis of muscle structure and function. The WSFP incorporates a soft, stretchable electrode array for high-performance electrophysiological monitoring with low contact impedance and high stability. Its innovative design absorbs skin deformation stress, ensuring stable adhesion of a flexible ultrasound transducer array, offering higher-fidelity imaging. With dynamic tissue imaging, it allows real-time visualization of muscle structure. The WSFP achieves superior accuracy in dynamic action recognition and disease assessment compared to single-modal methods, maintaining stable operation during motion for up to 72 hours. This study advances neuromuscular system analysis and improves diagnostic precision.

中文翻译：

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通过集成的多模态可穿戴贴片对动态神经肌肉系统进行原位结构-功能同步解剖


神经肌肉异常是成人残疾的主要原因。了解肌肉结构和功能之间的复杂相互作用对于有效的治疗和康复至关重要。然而，运动过程中肌肉的大幅变形（高达 40%）对准确评估构成了挑战。为了解决这个问题，我们开发了一种可穿戴的结构功能传感贴片 （WSFP），可以同步分析肌肉结构和功能。WSFP 采用柔软、可拉伸的电极阵列，用于高性能电生理监测，具有低接触阻抗和高稳定性。其创新设计可吸收皮肤变形应力，确保柔性超声换能器阵列的稳定粘附，从而提供更保真度的成像。通过动态组织成像，它可以实时可视化肌肉结构。与单模态方法相比，WSFP 在动态动作识别和疾病评估方面实现了卓越的准确性，可在运动期间保持稳定运行长达 72 小时。这项研究推进了神经肌肉系统分析，提高了诊断精度。