A tandem system comprising cyclization reaction of diazo compound and cross‐coupling of the other one has been developed. This provides facile access to pyrazoles and there derivatives with high levels of regioselectivity in moderate to good yields. This process uniquely utilizes CF3CH2OTf both as a solvent and a catalyst under mild conditions. Mechanistic studies provide insights into the intricate sequence involved in the formation of pyrazoles and further selective cross‐coupling with another diazo compound.

中文翻译：

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溶剂导向的区域选择性级联反应与重氮化合物


已经开发了一种串联系统，包括重氮化合物的环化反应和另一种化合物的交叉偶联反应。这提供了在中等至良好产量下获得具有高水平区域选择性的吡唑类和衍生物的简便途径。该工艺在温和条件下独特地利用 CF3CH2OTf 作为溶剂和催化剂。机理研究提供了对吡唑形成所涉及的复杂序列的见解，并进一步与另一种重氮化合物进行选择叉偶联。