In this work, a dual-responsive ionic liquid (DR-IL), namely, [C₄mim][FeCl₄] was developed for simultaneously extracting and separating hydrophilic phytochemicals, including epicatechin (EC), dihydroquercetin (DQ), ferulic acid (FA), and hydrophobic phytochemicals, such as emodin (ED), chrysophanol (CP), and physcion (PC), from roots of wild Rumex acetosa L. The [C₄mim][FeCl₄] demonstrates considerable potential for extracting and separating target phytochemicals through temperature adjustment and accelerated phase separation facilitated by a neodymium magnet. Meanwhile, a high recovery yield is obtained by adding a magnetic field. The overall extraction yield of target phytochemicals achieved by [C₄mim][FeCl₄] reaches 16.12 mg/g under the optimal extraction conditions, representing a 1.53–2.39-fold increase compared to conventional solvents. Furthermore, the molecular simulation and FT-IR analysis reveal that the synergistic effect of van der Waals forces and hydrogen bonds significantly contributed to the higher extraction yields of target phytochemicals.

中文翻译：

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智能双响应离子液体作为可转化和可回收的介质，用于从野生 Rumex acetosa L 中提取和分离植物化学物质。


在本工作中，开发了一种双响应离子液体 （DR-IL），即 [C₄mim][FeCl₄]，用于同时提取和分离亲水性植物化学物质，包括表儿茶素 （EC）、二氢槲皮素 （DQ）、阿魏酸 （FA） 和疏水性植物化学物质，如大黄素 （ED）、大黄酚 （CP） 和植酸素 （PC），来自野生 Rumex acetosa L 的根。[C₄mim][FeCl₄] 通过温度调节和钕磁铁促进的加速相分离，在提取和分离目标植物化学物质方面表现出相当大的潜力。同时，通过添加磁场可以获得高回收率。在最佳提取条件下，[C₄mim][FeCl₄] 实现的目标植物化学物质的总提取率达到 16.12 mg/g，比常规溶剂提高了 1.53-2.39 倍。此外，分子模拟和 FT-IR 分析表明，范德华力和氢键的协同作用显着促进了目标植物化学物质的较高提取率。