Organophosphorus (OPs) nerve agents, as a class of chemical warfare agents and widely used pesticides, are highly toxic synthetic chemicals that pose severe threats to human health and the environment. However, the current method of detoxifying OPs through hydrolysis cannot completely reduce their harmfulness, as the hydrolysis products of OPs are often highly toxic. Therefore, developing efficient deep detoxification catalysts is of great significance for the emergency response to OPs nerve agent leakage, deep purification of polluted environments, and ingenious construction of protective equipment. Herein, a bimetallic metal–organic gel (namely, Zr/Cu-TATAB) was designed and prepared through simple mixing of a reaction mixture of the Zr⁴⁺/Cu²⁺ salt and 2,4,6-tris[(p-carboxyphenyl)amino]-1,3,5-triazine (H₃TATAB) ligand at room temperature. The as-prepared Zr/Cu-TATAB with bimetallic active centers showed a deep detoxification effect toward methyl paraoxon (DMNP) via cascade degradation, in which the Zr(IV) node could efficiently degrade DMNP to p-nitrophenol (p-NP), while the Cu(II) node could further reduce the secondary product p-NP to the nontoxic and economically beneficial p-aminophenol (p-AP). This work demonstrated the great potential of the Zr/Cu-TATAB bifunctional cascade degradation system for deep detoxification of OPs nerve agents and provided new insights for the rational design of high-efficiency bifunctional catalysts in a simple way.

中文翻译：

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双功能金属-有机凝胶，用于通过级联降解过程对有机磷神经毒剂进行深度解毒


有机磷 （OPs） 神经毒剂是一类化学战剂和广泛使用的杀虫剂，是剧毒的合成化学品，对人类健康和环境构成严重威胁。然而，目前通过水解解毒 OPs 的方法并不能完全降低其危害性，因为 OPs 的水解产物通常具有剧毒。因此，开发高效的深度解毒催化剂对于应急应对OPs神经毒剂泄漏、污染环境深度净化、巧妙构建防护装备具有重要意义。在此，设计了一种双金属金属-有机凝胶（即 Zr/Cu-TATAB），通过在室温下将 Zr⁴⁺/Cu²⁺ 盐和 2,4,6-三[（对羧基苯基）氨基]-1,3,5-三嗪 （H₃TATAB） 配体的反应混合物简单混合制备。所制备的具有双金属活性中心的 Zr/Cu-TATAB 通过级联降解对甲基对氧克 （DMNP） 表现出深度解毒作用，其中 Zr（IV） 节点可以有效地将 DMNP 降解为对硝基苯酚 （p-NP），而 Cu（II） 节点可以进一步将副产物 p-NP 还原为无毒且经济有益的对氨基苯酚 （p-AP） 的这项工作证明了 Zr/Cu-TATAB 双功能级联降解系统在 OPs 神经毒剂深度解毒方面的巨大潜力，为高效双功能催化剂的合理设计提供了新的思路。