Cadmium (Cd) pollution poses a major threat to food safety. Sensitive detection of Cd²⁺ is of great significance for the life health. Herein, an aggregation-induced electrochemiluminescence (AIECL) sensor based on polymer dots (Pdots) is designed for Cd²⁺ detection. Through linkage of Cd²⁺ aptamer containing black hole quencher (BHQ) with Pdots, a signal “off” probe was achieved. In the presence of Cd²⁺, the BHQ moiety is released from Pdots and the ECL signal of Pdots is recovery. Such sensor exhibits excellent detection capability for Cd²⁺, with low detection limit of 0.006 ppb. More importantly, the sensor is applied for the quantitative analysis of Cd²⁺ in Ganoderma lucidum, and the results coincide well with the golden standard of ICP-MS. This study presents a facile and reliable methodology for the sensitive detection of cadmium, and demonstrates its potentials applying in food safety and environmental monitoring.

中文翻译：

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用于灵芝镉检测的高灵敏度聚集诱导电化学发光传感器


镉 （Cd） 污染对食品安全构成重大威胁。灵敏的 Cd ²⁺ 检测对生命健康具有重要意义。在此，设计了一种基于聚合物点 （Pdots） 的聚集诱导电化学发光 （AIECL） 传感器用于 Cd ²⁺ 检测。通过将含有黑洞淬灭基团 （BHQ） 的 Cd ²⁺ 适配体与 Pdots 连接，实现了信号“关闭”探针。在 Cd ²⁺ 存在的情况下，BHQ 部分从 Pdots 中释放出来，Pdots 的 ECL 信号是恢复。这种传感器表现出优异的 Cd ²⁺ 检测能力，检出限低至 0.006 ppb。更重要的是，该传感器用于灵芝中 Cd ²⁺ 的定量分析，结果与 ICP-MS 的金标准非常吻合。本研究提出了一种简便可靠的灵敏检测镉的方法，并展示了其在食品安全和环境监测中的应用潜力。