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Non-V600E BRAF mutations and treatment for Hairy Cell Leukemia.
Blood ( IF 21.0 ) Pub Date : 2024-12-24 , DOI: 10.1182/blood.2024026894 Evgeny Arons,Chin-Hsien Tai,Joshi Suraj,Yuelin Liu,Chi-Ping Day,Mark Raffeld,Liqiang Xi,Mory Gould,Isaac David Shpilman,Christopher C Oakes,Seema Ali Bhat,Michael Rhodes Grever,Daniel Jones,Kerry A Rogers,Hao-Wei Wang,Constance M Yuan,S Cenk Sahinalp,Robert J Kreitman
Blood ( IF 21.0 ) Pub Date : 2024-12-24 , DOI: 10.1182/blood.2024026894 Evgeny Arons,Chin-Hsien Tai,Joshi Suraj,Yuelin Liu,Chi-Ping Day,Mark Raffeld,Liqiang Xi,Mory Gould,Isaac David Shpilman,Christopher C Oakes,Seema Ali Bhat,Michael Rhodes Grever,Daniel Jones,Kerry A Rogers,Hao-Wei Wang,Constance M Yuan,S Cenk Sahinalp,Robert J Kreitman
We found 18 patients with immunophenotype consistent with classic hairy cell leukemia (HCL) and BRAF mutations other than just V600E. Twelve had 1 non-V600E BRAF mutation and 6 had V600E with 1 (n=5) or 2 (n=1) non-V600E BRAF co-mutations.
中文翻译:
非 V600E BRAF 突变和毛细胞白血病的治疗。
我们发现 18 例患者的免疫表型与经典毛细胞白血病 (HCL) 和 BRAF 突变一致,而不仅仅是 V600E。12 例有 1 个非 V600E BRAF 突变,6 例 V600E 有 1 个 (n=5) 或 2 个 (n=1) 个非 V600E BRAF 共突变。
更新日期:2024-12-24
中文翻译:
非 V600E BRAF 突变和毛细胞白血病的治疗。
我们发现 18 例患者的免疫表型与经典毛细胞白血病 (HCL) 和 BRAF 突变一致,而不仅仅是 V600E。12 例有 1 个非 V600E BRAF 突变,6 例 V600E 有 1 个 (n=5) 或 2 个 (n=1) 个非 V600E BRAF 共突变。