Loss of glomerular aldolase B in diabetic nephropathy promotes renal fibrosis via activating Akt/GSK/β-catenin axis,Journal of Advanced Research

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Loss of glomerular aldolase B in diabetic nephropathy promotes renal fibrosis via activating Akt/GSK/β-catenin axis
Journal of Advanced Research ( IF 11.4 ) Pub Date : 2024-12-24 , DOI: 10.1016/j.jare.2024.12.027
Minghui Liu, Wenwen Yang, Shuang Qu, Tingting Zhao, Song Jiang, Suming Peng, Mingchao Zhang, Ji Xuan, Zhihong Liu, Ke Zen

Diabetic nephropathy (DN), characterized by a complex and multifaceted pathogenesis, stands as the foremost catalyst behind end-stage renal disease (ESRD). This study aims to analyze the level and non-metabolic role of glomerular aldolase B (ALDOB) in DN progression.

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