The adhesion and proliferation of bacteria on textiles can lead to unacceptable cross‐infection and potential contamination. Herein, an antimicrobial and anti‐adhesive textile is prepared through enzymatic redox‐mediated fabrication of nanosilver‐embedded polydisulfide networks. Specifically, γ‐methacryloyloxypropyltrimethoxysilane is introduced to cotton fibers to build a reactive hydrophobic layer. Subsequently, α‐lipoic acid‐modified tyramine (mTA) is oxidized using horseradish peroxidase and enzymatically grafted onto the vinylated cotton, producing brown polyphenols containing dynamic disulfide bonds. Ultimately, in situ reduction and entrapment of nanosilver are accomplished by the sulfhydryl groups generated from mTA units, forming an antimicrobial network on fiber surfaces. After contact with bacteria for 30 min or fungi for 3 h, the antibacterial rates of the resulting fabric both reach 99.99%. Benefiting from the encouraging photothermal conversion property, bacteria and fungi on fabric surfaces can be killed after 10 min of irradiation at 100 mW cm−2, demonstrating multimode synergistic antibacterial activity. Strikingly, the fabric has impressively durable antimicrobial and bacterial anti‐adhesive properties, maintaining a high bactericidal efficiency after cyclic bacterial contamination tests. Besides, in situ coloring of the fabric is realized while maintaining its inherent wearability, accompanying by satisfactory biocompatibility and hemocompatibility. The presented work provides novel insights into the design and construction of highly efficient antimicrobial textiles.

中文翻译：

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通过将纳米银嵌入动态聚二硫键网络中，酶促氧化还原介导的具有多模式协同抗菌活性的纺织品


细菌在纺织品上的粘附和增殖会导致不可接受的交叉感染和潜在的污染。在此，通过酶促氧化还原介导的纳米银嵌入聚二硫键网络的制造制备了一种抗菌和抗粘连纺织品。具体来说，将 γ-甲基丙烯酰氧丙基三甲氧基硅烷引入棉纤维中以构建反应性疏水层。随后，α-硫辛酸修饰的酪胺 （mTA） 使用辣根过氧化物酶被氧化并酶促接枝到乙烯基化棉花上，产生含有动态二硫键的棕色多酚。最终，纳米银的原位还原和捕获是通过 mTA 单元产生的巯基完成的，从而在纤维表面形成抗菌网络。与细菌接触 30 分钟或与真菌接触 3 小时后，所得织物的抗菌率均达到 99.99%。得益于令人鼓舞的光热转化特性，在 100 mW cm-2 下照射 10 分钟后，织物表面的细菌和真菌可以被杀死，显示出多模式协同抗菌活性。引人注目的是，这种面料具有令人印象深刻的耐用抗菌和抗菌抗粘附性能，在循环细菌污染测试后仍能保持高杀菌效率。此外，在保持其固有耐磨性的同时实现织物的原位着色，并伴有令人满意的生物相容性和血液相容性。所介绍的工作为高效抗菌纺织品的设计和构建提供了新的见解。