Hydroxylamine-derived active esters were synthesized from oseltamivir, which can serve as practical synthetic handles to prepare oseltamivir analogs. Succinimide-based active ester was the most effective derivative for synthesizing a series of oseltamivir carboxamides.

中文翻译：

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利用基于 N-羟胺的活性酯合成奥司他韦酰胺衍生物


羟胺衍生的活性酯由奥司他韦合成，可作为制备奥司他韦类似物的实用合成手柄。基于琥珀酰亚胺的活性酯是合成一系列奥司他韦羧酰胺最有效的衍生物。