We developed a metal- and oxidant-free electrochemical method for direct alkoxylation of benzylic C(sp³)−H bonds, producing only hydrogen as a by-product. This method efficiently functionalizes a wide range of alcohols, enabling the synthesis of celestolide and diphenhydramine derivatives.

中文翻译：

---

苄基 C（sp3）−H 键的电化学烷氧基化


我们开发了一种不含金属和氧化剂的电化学方法，用于苄基 C（sp³）-H 键的直接烷氧基化反应，仅产生氢气作为副产品。该方法可有效地官能化多种醇类，从而能够合成天青内酯和苯海拉明衍生物。