Results of the STEP 9 trial show that semaglutide leads to improvements in knee osteoarthritis-related symptoms. The findings support weight-management pharmacotherapies as a feasible option for management of knee osteoarthritis, but cost-effectiveness, risk of toxicity and likelihood of rebound must be considered.

中文翻译：

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膝骨关节炎和超重或肥胖患者的精确体重管理


STEP 9 试验的结果表明，索马鲁肽可改善膝骨关节炎相关症状。研究结果支持体重管理药物治疗是治疗膝骨关节炎的可行选择，但必须考虑成本效益、毒性风险和反弹的可能性。