This study aims to examine the restorative impact of corn cob biochar (CCB) on pendimethalin (PMD)-induced toxicity in Oreochromis niloticus. Fish were divided into four groups: the first control group without treatment, the second group (CCB) exposed to 10 g CCB/L, the third group (PDM) exposed to 0.355 mg PDM/L, and the fourth group (PDM+ CCB) receiving both 0.355 mg PDM/L and 10 g CCB/L for 30 days. PDM exposure resulted in behavioral alterations, low survival rate (73.33 %), hematological and biochemical impairments, increased oxidative stress, suppressed immunity, and histopathological damage in gill, liver, and brain tissues. Co-treatment with CCB significantly alleviated these effects, as evidenced by improved survival rate (88.88 %), hematological, biochemical, and antioxidant-immune parameters and reduced histopathological alterations. In conclusion, CCB demonstrated a promising potential to mitigate PDM-induced toxicity in O. niloticus by enhancing physiological, biochemical, and histological resilience.

中文翻译：

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玉米芯生物炭对减轻尼罗罗非鱼 （Oreochromis niloticus） 中二甲戊灵诱导的毒性的潜在影响：对血液学、生化、抗氧化免疫参数和组织病理学改变的影响


本研究旨在检验玉米芯生物炭 （CCB） 对二甲戊灵 （PMD） 诱导的尼罗河毒株毒性的修复影响。将鱼分为四组：第一组未处理，第二组 （CCB） 暴露于 10 g CCB/L，第三组 （PDM） 暴露于 0.355 mg PDM/L，第四组 （PDM+ CCB） 接受 0.355 mg PDM/L 和 10 g CCB/L，持续 30 天。PDM 暴露导致行为改变、存活率低 （73.33%）、血液学和生化损伤、氧化应激增加、免疫抑制以及鳃、肝和脑组织的组织病理学损伤。与 CCB 的共同治疗显着减轻了这些影响，存活率提高 （88.88%） 、血液学、生化和抗氧化免疫参数以及减少组织病理学改变证明了这一点。总之，CCB 显示出通过增强生理、生化和组织学弹性来减轻 PDM 诱导的尼罗河毒株毒性的潜力。