The Front Cover illustrates a new member of the heteroenediyne group obtained through Nicholas cyclization. Although thiaenediyne is the least reactive in the Bergman cyclization, its appearance allows the application of NBO analysis to the entire family of benzothiophene-conjugated heteroenediynes, thus substantiating the major role of the heteroatom in the enediyne moiety for the reactivity of enediynes in the Bergman cyclization. More details can be found in the Research Article by I. A. Balova and co-workers (DOI: 10.1002/ejoc.202401127).

中文翻译：

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封面：填补 10 元异二炔内的空白：Thiaenediyne – 一项实验和理论研究 （Eur. J. Org. Chem. 47/2024）


封面展示了通过 Nicholas 环化获得的 heteroenediyne 基团的新成员。尽管噻二炔在 Bergman 环化中反应性最低，但它的出现允许将 NBO 分析应用于整个苯并噻吩共轭异烯二炔家族，从而证实杂原子在 enediyne 部分对 Bergman 环化中烯二炔反应性的主要作用。更多详细信息可以在 I. A. Balova 及其同事的研究文章 （DOI： 10.1002/ejoc.202401127） 中找到。